Epidemiology Breast cancer prognosis in relation to family history of breast and ovarian cancer L Thalib1, S Wedrén2, F Granath2, H-O Adami2, B Rydh2, C Magnusson2 and P Hall2 1Department of Community Medicine and Behavioural Science (Biostatistics), Faculty of Medicine, Kuwait University, Box 24923, Safat 13110, Kuwait 2Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 171 77 Stockholm, Sweden Correspondence to: Dr S Wedrén, E-mail: Sara.Wedren@meb.ki.se We linked four nationwide Swedish population-based registries to identify first-degree family history of breast and ovarian cancer among breast cancer cases diagnosed between 1991 and 1998 and followed them until death, emigration or end of follow-up in December 1998. The median follow-up was 36 months. Using Cox proportional hazards models, the hazard ratio of death (HR) due to breast cancer was estimated. Women with a family history of breast or ovarian cancer (n=2175, 12.7%) had a nonsignificantly better prognosis than women without any family history, HR 0.86 (95% CI 0.71-1.05); this appeared unrelated to age at diagnosis either in the index case or in relative(s) with breast and/or ovarian cancer. Our study shows that prognostic outlook is not worse among breast cancer patients with family history. British Journal of Cancer (2004) 90, 1378-1381. doi:10.1038/sj.bjc.6601694 Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.