MEDSCAPE Except from: 8th International Conference on Primary Therapy of Early Breast Cancer; March 12-15, 2003; St. Gallen, Switzerland "It seems clear that women who develop breast cancer during pregnancy may present with a higher stage due to delay in diagnosis, but that once matched stage for stage with other women, they do no worse.[34] In addition, it has been suggested that physicians should recommend that women do not become pregnant for several years after a diagnosis of breast cancer, but that following that interval, pregnancy may not affect their outcome. Unfortunately, much of these data are anecdotal, as women who become pregnant following breast cancer are a highly select group and are not typically randomized to treatment." 34.Mouridsen HT, Kroman N. Pregnancy before and after breast cancer. Program and abstracts of the 8th International Conference on Primary Therapy of Early Breast Cancer; March 12-15, 2003; St. Gallen, Switzerland. Abstract S32. Author:Kathleen I. Pritchard, MD, Professor, Department of Medicine, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada 11/02 A recent study/survey of National Cancer Institute-designated cancer centers showed that 14% offer counseling on fertility and sexual issues. EDITORIAL: Cancer during Pregnancy [07/11/99; New England Journal of Medicine] Cancer is rare during pregnancy, occurring in only about 1 per 1000 live births. More than half the cases are tumors of the uterine cervix, breast, or thyroid, which can metastasize to the placenta but not the fetus. Melanoma and hematologic tumors, which also can invade the placenta, may cross into the fetal circulation. In a recent review, Baergen et al. described 19 cases of maternal melanoma that had metastasized to the placenta. In five of these cases the tumor extended into the fetus, which died of metastatic melanoma in four of the five cases. The transmission of maternal leukemia to the fetus has been documented by immunologic similarities between the leukemic cells in the mother and those in the fetus. The report in this issue of the Journal by Catlin et al. clearly shows that an aggressive lymphoma can enter the fetal circulation and affect the fetus. The authors point out that the mother in the case they studied was not homozygous for the male fetus's HLA haplotypes and the fetus was not immunocompromised, making it likely that the lymphoma, a highly aggressive tumor, grew without hindrance by the fetus's immature immunologic system. J Clin Oncol, 3/01 Relation of Reproductive Factors to Mortality from Bca Obstetricians Should Do Breast Exams Mgment & Clinical Outcomes Pregnant Pts w/Inv Cervical Ca Cancer Treatment Reviews March 2001 Vulnerable Women's Eggs Irradiated Uterus & Pregnancy Issues J Human Reproduction, March 01, study of mice Assessement of Fetal Risk Assoc w/Exposure to Chemo Chemo May be Safe for Some Pregnant Women Pregnancy Issues with Imatinib Journal Fertility/Sterility April, 2001 Short Burst Tam & Fertility Oncologist and Sperm Banking Before Treatment Information Needs for Younger Women Evidence of Herb/Drug Interaction w/Contraceptives Ovarian Tissue Frozen, Embryo Obtained Later Preservation: Fertility in Young Women w/Cancer Experimental Surgery: Cervical Trachelectomy Female Infertility & Wirn Technique-Manual Phys Thrpy Live Birth After Orthotopic Transplantation Fertility, Gonadal & Sexual Function: AFTER Testicular Ca Pregnancy Possible After Cervical Surgery Am J of Epidemiology, June 2001 Am J of Epidemiology, 6/01 Lifetime Lactation: Korean Women's Cohort Breast-feeding & Risk Reduction BRCA1/BRCA2 LINK - Almost 8 months pregnant at diagnosis Int'l J of Cancer, May,2001 Abortion & BC-Review Finds Insufficient Data Judge Dismisses Suit Attempting to Link Bca/Abortions Bca/Abortion in Chinese Women (China) Abortions/Bca:Records-based Case-Control Study Abortion & Breast Cancer:NYTimes Editorial Induced/Spontaneous Abortion & Bca Risk: None Contraceptive methods, Induced Abortion & Colon Ca LINK nonprofit organization dedicated to providing reproductive information, support and hope to cancer patients American Roetgen Ray Society, 5/02 LINK evidence-based information on safety/risk of drugs, chemicals & disease during pregnancy/lactation. Euro Soc for Human Reproduction & Embryology, 7/02 Pediatric CA & Subsequent Pregnancy Increased Risk of Bca w/RTX-Hodgkin's & Pregnancy The Oncologist, 8/02 Overview from Senologist Recent Developments:Cancer/Pregnancy Chemo-induced Amenorrhea/Fertility Bca in Pregnancy:Literature Review Lactation & Mammograms Pregnancy SAFE for Cancer Survivors & Babies Pregnancy, breast ca characteristics, receptor status Imatinib Use During Pregnancy May Cause Serious Fetal Abnormalities LINK to organization for Pregnant Women with cancer Obstetrical & Gynecological Survey, Janaury, 2001 SYLK Psycho-Oncology, 6/03 Pilot Intervention: Enhance Sexual Rehab After Prostate Ca Sexual Functioning after Testicular Cancer Brit J Cancer, 10/03 Articles/studies Zingiber officinale (GINGER) as Antiemetic Ginger for Nausea/Vomiting (Pregnancy) Element of Ginger Triggers Cell Death, Enhances Cisplatin Ginger in prevention of nausea/vomiting after major GYN surgery ASCO, 2004 Acta Obstetricia et Gynecologica Scandinavica, 3/04 The Breast, 12/04 Article in Spring 2003 CBCRP newsletter Lancet. 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