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ABSTRACT: Familial risk factors for breast cancer among Arab women
in Israel
The incidence of breast cancer in Arab women is low compared
with western populations in other countries. Very few studies on
risk factors for breast cancer in Arab women have been reported.
The aim of the present study was to evaluate familial risk factors
for breast cancer among Arab women in Israel.
A case.control study
was carried out on 72 Arab women diagnosed with breast cancer and
140 healthy controls. Cases were identified through oncology wards
and controls were sampled from community and hospital out-patient
clinics. All participants were interviewed and information obtained
on family history of breast cancer and other cancers, and other
potential risk factors.
Eight women with breast cancer and five
women without breast cancer had a first-degree relative with breast
cancer. The odds ratio for breast cancer for a woman with a
first-degree relative with breast cancer was 3.4 (95% confidence
interval (CI) 1.06.10.7, P = 0.04).
The odds ratio for Muslim women
with a first-degree relative with breast cancer was higher than that
for Christian women (6.07 and 1.53, respectively).
Family history of
breast cancer was a risk factor for breast cancer in Arab women. The
estimated relative risk associated with an affected first-degree
relative was generally higher than that reported from other populations.
[10/10/2002; European Journal of Cancer Prevention]
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