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Folinic Acid Part of Colorectal Therapy

In a new magazine called Cure,Cancer Updates, Research & Education, I found a mention of a trial on colorectal cancer using "Triple Drug Therapy" compared to a regimen using Oxaliplatin with fluorouracil and folinic acid (Folfox).

The article stated that: "A preliminary analysis showed that Folfox could be a good option for advanced colorectal cancer, with good results seen in terms of producing tumor shrinkage, in prolonging the time until cancer progression, and in prolonging survival.

Folfox was also associated with fewer side effects than the Triple Drug Therapy, particularly severe diarrhea.

At this time the FDA recommends Triple Drug Therapy as its approved option for metastatic colonrectal cancer patients. Oxaliplatin is approved for use only in Europe and Asia.

However trials in the United States that could lead to approval of oxaliplatin are nearing completion and discussions are ongoing between the manufacturer and the FDA to make oxaliplatin available to more patients on a compassionate basis until the time where it is approved for widespread use.

From Cure, Summer, 2002 www.curetoday.com


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padAnn Fonfa's Ltr to Cure Magazine
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July 7, 2002 Suggesting coverage of CAM
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