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Fruit and Vegetable Consumption and Risk of Lung Cancer
"Fruit and vegetable consumption and lung cancer risk: updated information from the European Prospective Investigation into Cancer and Nutrition (EPIC),"
Linseisen J, Rohrmann S, et al,
(Address: Jakob Linseisen, German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany. E-mail: j.linseisen@dkfz.de ).
Summary: In a study analyzing diet and lifestyle data from 478,590 individuals (participants in the European Prospective Investigation into Cancer and Nutrition), fruit consumption was found to be inversely associated with lung cancer incidence in the entire cohort and vegetable consumption was found to be inversely associated with lung cancer among smokers.
Over a median 6.4 years of follow up, 1,126 cases of lung cancer were reported. Fruit consumption was associated with a reduced risk of lung cancer in the entire cohort (hazard ratio: 0.92 per 100 g increase in daily fruit consumption), and among smokers (HR: 0.90).
While vegetable consumption was not associated with a reduced risk of lung cancer in the cohort as a whole, it was significantly associated with a reduced risk among smokers (HR: 0.78 per 100 g increase in daily vegetable consumption).
In the entire cohort, the incidence of cancer decreased as consumption of apples and pears increased and among smokers, the inciden ce of cancer decreased as consumption of root vegetables increased.
The results of this study suggest that dietary factors may be associated with the incidence of lung cancer, with increasing fruit and vegetable consumption exerting protective effects.
Int J Cancer, 2007; 121(5): 1103-14.
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