Head/Neck (Oral) Cancer

April 2009

According to study published online March 16 in the Journal of Clinical Oncology, smoking, excessive alcohol use, a low consumption of fruit, and inadequate physical activity were associated with lower rates of survival.

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April 2008 – Please see this interesting article shown below:

“Pretreatment Swallowing Exercises Benefit Head and Neck Cancer Patients”

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Postsurgery enteral nutrition in head and neck cancer patients.

De Luis DA, Aller R, Izaola O, Cuellar L, Terroba MC

Institute of Endocrinology and Nutrition, Medicine School and Hospital Rio Hortega, Spain.

OBJECTIVE: Patients with head and neck cancer undergoing surgery have a high incidence of postoperative complications.

The aim of our study was to investigate whether postoperative nutrition of head and neck cancer patients, using an arginine-enriched diet, could improve nutritional variables as well as clinical outcomes.

DESIGN: Randomized clinical trial.

SETTING: Tertiary care. SUBJECTS: A population of 47 patients with oral and laryngeal cancer were enrolled.

INTERVENTIONS: At surgery patients were randomly allocated to two groups: (a) patients receiving an enteral diet supplemented with arginine and fiber (group I); (b) patients receiving an isocaloric, isonitrogenous enteral formula (group II).

RESULTS: No significant intergroup differences in the trend of the three plasma proteins and lymphocytes were detected. Gastrointestinal tolerance (diarrhea) of both formulas was good (17.4% group I and 8.3% group II; NS).

During the 3 months after hospital discharge five patients died; no diferences were detected between groups (13% group I and 8.3% group II; NS). The incidences postoperative infection complications were similar (nine patients) in both groups (21.7% group I and 16.7% group II; NS).

Fistula were less frequent in enriched nutrition group (0% group I and 20.8% group II; P<0.05); wound infection was more frequent in group II, but without statistical difference (4.3% group I and 12.5% group II; NS). The length of postoperative stay was 22.8+/-11.8 days in the enriched group and 31.2+/-19.1 days in the control group (P=0.07).

CONCLUSIONS: In conclusion, enriched formula improves local wound complications in postoperative head and neck cancer patients. Our results suggest that these patients could benefit from an immunonutrient-enhanced enteral formula.

Eur J Clin Nutr 2002 Nov;56(11):1126-9

Pretreatment Swallowing Exercises – Improve Head/Neck CA Pts

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