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American Oncologists May Not Regard Clinical Trials

How American oncologists treat breast cancer: an assessment of the influence of clinical trials.

Belanger D, Moore M, Tannock I.

Department of Medicine, Princess Margaret Hospital, Toronto, Ontario, Canada.

The present study was designed to assess the preferred methods of treatment of breast cancer by American oncologists, and the impact of clinical trials on their practice.

We mailed 465 questionnaires to surgical, radiation, or medical oncologists. The questionnaire described five hypothetic patients with breast cancer, and respondents were asked to select their preferred treatment for each patient. ...

Our report suggests that even large randomized clinical trials may have a minimal impact on practice if their results run counter to belief in the value of the treatment.

J Clin Oncol 1991 Jan;9(1):7-16

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