Soy protein isolate consumption protects against azoxymethane-induced colon tumors in male rats. Hakkak R, Korourian S, Ronis MJ, Johnston JM, Badger TM. Arkansas Children's Nutrition Center, University of Arkansas for Medical Sciences, 1120 Marshall Street, Little Rock, AR 72202, USA. hakkakreza@uams.edu Male Sprague-Dawley rats (F2 generation) that had been fed modified American Institute of Nutrition-93G diets formulated with a single protein source of either casein or soy protein isolate for their entire life received azoxymethane once a week for 2 weeks (s.c., 15 mg/kg) starting at age 90 days. Forty weeks later, all rats were euthanized, the colon was examined visually for masses and these were subsequently evaluated histologically. Rats fed the casein diet had a 50% incidence of colon tumors compared with 12% on soy protein-based diets (P<0.05). These results suggest that consumption of soy protein-containing diets may reduce the risk of developing colon tumors. Cancer Lett 2001 May 10;166(1):27-32 PMID: 11295283 [PubMed - indexed for MEDLINE] Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.