Recreational physical activity and risk of papillary thyroid cancer (United States) Mary Anne Rossing Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North (MP-381), Seattle, WA, USA Rachel Remler Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North (MP-381), Seattle, WA, USA Lynda F. Voigt Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North (MP-381), Seattle, WA, USA Kristine G. Wicklund Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North (MP-381), Seattle, WA, USA Janet R. Daling Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North (MP-381), Seattle, WA, USA Abstract Objective: Exercise has been hypothesized to influence cancer risk through a variety of mechanisms including hormonal, metabolic and immunologic effects, yet its relation with the risk of thyroid cancer has not been examined. We conducted a population-based case–control study in women aged 18–64 in three counties of western Washington State to assess the relation of recreational physical activity with risk of papillary thyroid cancer. Methods: Of 558 women with thyroid cancer of the follicular epithelium diagnosed during 1988–1994 who were identified as eligible, 468 (83.9%) were interviewed; this analysis was restricted to women with papillary histology (n = 410). Controls (n = 574) were identified by random digit dialing, with a response proportion of 73.6%. Logistic regression was used to calculate odds ratios (OR) and associated confidence intervals (CI) estimating the relative risk of papillary thyroid cancer associated with various aspects of recreational exercise. Results: Risk of thyroid cancer was reduced among women who reported that they engaged in regular recreational exercise during the 2 years before diagnosis relative to women who did not report exercise during that time period (OR = 0.76, 95% CI 0.59–0.98). A similar risk reduction was noted among women who reported having exercised regularly between ages 12 and 21 (OR = 0.83, 95% CI 0.64–1.1). However, no clear associations with aspects of recreational activity, including average hours exercised per week or weekly energy expenditure, were observed. Conclusions: These results provide some initial support for the hypothesis that physical activity may reduce risk of thyroid cancer. Cancer Causes and Control 12 (10): 881-885, December 2001 Copyright © 2001 Kluwer Academic Publishers All rights reserved Article ID: 358974 Contact info here,9/04 Euro J Cancer Prevent, 6/03 Hem/Onc News, 4/03 Second Primary Malignancies: Thyroid Ca Salivary Gland Toxicity after Radioiodine Thrpy Thyroid Ca What's the Best Way to Detect Cancer Recurrence After a Thryoidectomy? Am J Surgery, 12/03 Evidence-based Guidelines for Thyroid Nodules Nucl Med. Commun, 6/03 Share w/your doctor Pre-treatment w/rhTSH Reduces Retention of 131I) J Clin Pharm & Thera, 2/04 Various abstracts ASCO, 2004 Outcome of Well Differentiated Thyroid Ca: Turkey Well Differentiated Thyroid Ca: Ten Years Experience Clin Analysis Thryoid Ca: Chernobyl-exposed Adults JAMA, 1.204 variety of links J Surg Oncol, 12/06 Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.