
Vitamin A derivative may be useful in fighting cancer
An experimental drug derived from vitamin A may be useful in fighting neuroblastoma when other chemotherapy drug fails. Neuroblastomas are highly malignant tumors that arise in nervous system tissue and are usually diagnosed in infants or young children. The tumors usually spread rapidly to the lymph nodes, liver, lung and bone.
The drug, known as fenretinide or 4-HPR, induced laboratory-grown neuroblastoma cells to undergo apoptosis, a cell suicide program, according to a report in the Journal of the National Cancer Institute.
07/11/99 Reuters News Service
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